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D3R ligand 1

This compound is a potent and selective dopamine D3 receptor antagonist (Ki=66 nM) based on a THPB scaffold. It blocks both G-protein and β-arrestin signaling pathways, making it a useful research tool for studying D3 receptor function in substance use disorders and Parkinson's disease in both cellular and animal models.

Product Specifications

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C27H37NO5

Molecular Weight

455.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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