D3R ligand 1
This compound is a potent and selective dopamine D3 receptor antagonist (Ki=66 nM) based on a THPB scaffold. It blocks both G-protein and β-arrestin signaling pathways, making it a useful research tool for studying D3 receptor function in substance use disorders and Parkinson's disease in both cellular and animal models.
Product Specifications
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Molecular Formula
C27H37NO5
Molecular Weight
455.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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