PD-1/PD-L1-IN-31

PD-1/PD-L1-IN-31 is a high-affinity small molecule inhibitor (IC50=2.2 nM) of the PD-1/PD-L1 immune checkpoint. It promotes IFN-γ production and activates PBMCs, leading to restored T-cell-mediated tumor cell killing in vitro, making it a valuable tool for immuno-oncology research.