Anticancer agent 139
Compound 6h (Anticancer Agent 139) is a potent tubulin-binding small molecule, engaging Lys352 via π-cation interaction. It demonstrates high growth inhibition in SNB-19, OVCAR-8, and NCI-H460 cells, with broader moderate activity across multiple other cancer cell lines, supporting its use in anticancer mechanism and cytotoxicity studies.
Product Specifications
Field of Research
Signal Transduction
Molecular Formula
C16H12F3N3O
Molecular Weight
319.28
Storage Conditions
-20°C
Notes
For research use only.
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