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BWA-522

BWA-522 is an orally bioavailable PROTAC degrader targeting the androgen receptor's N-terminal domain, inducing apoptosis in prostate cancer cells. It effectively degrades both AR-FL and AR-V7 splice variants, demonstrating significant tumor growth inhibition in LNCaP xenograft models and reducing receptor levels in VCaP and LNCaP cell lines.

Product Specifications

Field of Research

Cell Biology, Metabolism Research

Molecular Formula

C43H51ClN4O7

Molecular Weight

771.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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