JT002
JT002 is an orally bioavailable small molecule inhibitor of the NLRP3 inflammasome. It blocks NLRP3 complex assembly, reducing IL-1β, IL-18, and pyroptosis, and has demonstrated efficacy in murine models of airway hyperresponsiveness and neutrophilic inflammation.
Product Specifications
CAS Number
2238820-43-2
Field of Research
Immunology & Inflammation
Smiles
N (C (NS (=O) (=O) C1=C2N (N=C1) C[C@H] (OC) CO2) =O) C3=C4C (=CC5=C3CCC5) CCC4
Molecular Formula
C20H24N4O5S
Molecular Weight
432.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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