CP-07

CP-07 is a potent and selective PROTAC-based CDK9 degrader with a DC50 of 43 nM. It inhibits prostate cancer cell proliferation and colony formation in vitro (e.g., 22RV1 cells; IC50: 62 nM) and suppresses xenograft tumor growth in vivo by reducing Mcl-1 and c-Myc protein levels, making it a valuable tool for oncology research.