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Nrf2-IN-3

Nrf2-IN-3 is a selective inhibitor that targets mutant KEAP1, restoring its ability to repress NRF2 signaling. This compound has been shown to enhance cisplatin sensitivity in mouse xenograft models of mKEAP1 cancer, supporting its use in oncology research for investigating the KEAP1/NRF2 pathway in vitro and in vivo.

Product Specifications

CAS Number

6325-13-9

Product Name Alternative

NRF2

Field of Research

Immunology & Inflammation

Purity

98.07% (May vary between batches)

Solubility

DMSO:100 mg/mL (225.97 mM)

Smiles

O=C (NN=CC=1C=CC=CC1O) CCCSCCCC (=O) NN=CC=2C=CC=CC2O

Molecular Formula

C22H26N4O4S

Molecular Weight

442.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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