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CGAS-IN-1

CGAS-IN-1 (C20) is a flavonoid-based inhibitor of the Cyclic GMP-AMP Synthase (cGAS) enzyme, showing IC50 values of 2.28 μM (human) and 1.44 μM (mouse) . It is a research tool for studying the cGAS-STING pathway in autoimmune and inflammatory disease models, with applications in both in vitro biochemical assays and cellular research.

Product Specifications

CAS Number

858770-07-7

Field of Research

Immunology & Inflammation, Infectious Disease & Virology

Smiles

COC1=CC=C2C (OC (=O) C (CCC (=O) N (CC (O) =O) CC (O) =O) =C2C) =C1

Molecular Formula

C18H19NO8

Molecular Weight

377.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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