CGAS-IN-1
CGAS-IN-1 (C20) is a flavonoid-based inhibitor of the Cyclic GMP-AMP Synthase (cGAS) enzyme, showing IC50 values of 2.28 μM (human) and 1.44 μM (mouse) . It is a research tool for studying the cGAS-STING pathway in autoimmune and inflammatory disease models, with applications in both in vitro biochemical assays and cellular research.
Product Specifications
CAS Number
858770-07-7
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Smiles
COC1=CC=C2C (OC (=O) C (CCC (=O) N (CC (O) =O) CC (O) =O) =C2C) =C1
Molecular Formula
C18H19NO8
Molecular Weight
377.35
Storage Conditions
-20°C
Notes
For research use only.
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