Lysyl hydroxylase 2-IN-1

Lysyl Hydroxylase 2-IN-1 (compound 12) is a potent and selective LH2 inhibitor with an IC50 of ~300 nM, showing minimal activity against LH1 and LH3. This tool compound is valuable for investigating LH2's role in collagen cross-linking in fibrotic disease models, both in cellular assays and animal studies.