PPM-3
PPM-3 is a potent and selective PROTAC degrader of ERK5 with an IC50 of 62.4 nM. It modulates tumor progression by influencing macrophage differentiation rather than through direct cytotoxicity, making it a valuable tool for immuno-oncology research in both cellular and animal models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C54H69N11O6S
Molecular Weight
1000.26
Storage Conditions
-20°C
Notes
For research use only.
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