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PPM-3

PPM-3 is a potent and selective PROTAC degrader of ERK5 with an IC50 of 62.4 nM. It modulates tumor progression by influencing macrophage differentiation rather than through direct cytotoxicity, making it a valuable tool for immuno-oncology research in both cellular and animal models.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C54H69N11O6S

Molecular Weight

1000.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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