AD186
AD186 is a potent and selective sigma-1 receptor (S1R) agonist with high affinity (Ki = 2.7 nM) and 10-fold selectivity over the sigma-2 receptor. It serves as a valuable pharmacological tool for investigating S1R function in neuropathic pain models, as evidenced by its ability to reverse the antiallodynic effects of BD-1063 in vivo.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Formula
C22H28N2
Molecular Weight
320.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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