Antimalarial agent 27
This potent antimalarial small molecule (compound 11a) exhibits an IC50 of 0.37 μM against P. falciparum by selectively targeting the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM. It serves as a valuable chemical probe for studying isoprenoid biosynthesis in malaria parasites in both cellular and biochemical assays.
Product Specifications
Field of Research
Infectious Disease & Virology
Molecular Formula
C10H11NNaO5P
Molecular Weight
279.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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