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Antimalarial agent 27

This potent antimalarial small molecule (compound 11a) exhibits an IC50 of 0.37 μM against P. falciparum by selectively targeting the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM. It serves as a valuable chemical probe for studying isoprenoid biosynthesis in malaria parasites in both cellular and biochemical assays.

Product Specifications

Field of Research

Infectious Disease & Virology

Molecular Formula

C10H11NNaO5P

Molecular Weight

279.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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