GSK737
GSK737 is a potent dual BET bromodomain inhibitor, targeting both BD1 (pIC50 5.3) and BD2 (pIC50 7.3) of BRD4. It is characterized by favorable pharmacokinetic properties, including low clearance, good solubility, and permeability, making it a suitable chemical probe for in vitro and in vivo studies of BET protein function in oncology and inflammation research.
Product Specifications
CAS Number
2748687-95-6
Field of Research
Epigenetics & Chromatin
Smiles
O ([C@@H] (C) C1=CC=CC=N1) C2=C (C=C (C (NC3CC3) =O) C=C2) C=4N=NN (C) C4
Molecular Formula
C20H21N5O2
Molecular Weight
363.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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