ATR-IN-22
ATR-IN-22 (Compound 34) is an orally bioavailable ATR inhibitor with potent in vitro anti-proliferative activity, showing an IC50 below 1 μM in MIAPaCa-2 pancreatic cancer cells. It has also demonstrated in vivo anti-tumor efficacy in colon cancer models, supporting its use in oncology research targeting DNA damage response pathways.
Product Specifications
CAS Number
2905312-07-2
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C (#N) C1 (C=2C3=C (C (=NC=C3) C=4C=CNN4) N=C (C2) N5[C@H] (C) COCC5) CCC (N (C) C) CC1
Molecular Formula
C25H31N7O
Molecular Weight
445.56
Storage Conditions
-20°C
Notes
For research use only.
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