JBI-589
JBI-589 is a selective, non-covalent PAD4 inhibitor that reduces CXCR2 expression and neutrophil migration. It has been shown in research to suppress primary tumor growth and metastasis in vivo, and can enhance the activity of immune checkpoint blockade therapies.
Product Specifications
CAS Number
2308504-22-3
Field of Research
Epigenetics & Chromatin
Smiles
C (N1C (=CC=2C1=CC=CC2) C3=C (C) N4C (=N3) C=C (C (=O) N5C[C@H] (N) CCC5) C=C4) C6=CC=C (F) C=C6
Molecular Formula
C29H28FN5O
Molecular Weight
481.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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