PROTAC IRAK4 degrader-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a potent heterobifunctional degrader of IRAK4, demonstrating an IC50 of 15.5 nM. This tool compound is valuable for investigating IRAK4's role in oncology and immunology research, supporting both in vitro cellular studies and in vivo preclinical models of inflammation and cancer.
Product Specifications
CAS Number
2911615-06-8
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (=O) (N1CCC2 (CC1) CCN (C[C@H]3CC[C@@H] (CC3) N4C=C (NC (=O) C5=C6N (N=C5) C=CC (=N6) N7[C@@]8 (C[C@] (C7) (OC8) [H]) [H]) C (C (F) F) =N4) CC2) C9=CC (=C (Cl) C=C9) N%10C (=O) NC (=O) CC%10
Molecular Formula
C43H50ClF2N11O5
Molecular Weight
874.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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