BVFP
BVFP is a small molecule inhibitor that disrupts the interaction between progranulin (PGRN) and its neuronal receptor sortilin (SORT1) . By blocking this binding and subsequent endocytosis, it elevates extracellular PGRN levels, showing therapeutic promise for frontotemporal dementia (FTLD-TDP) in research models.
Product Specifications
CAS Number
357158-20-4
Product Name Alternative
NeurotensinReceptor, Neurotensin Receptor
Field of Research
Pharmacology & Drug Discovery
Purity
98.74% (May vary between batches)
Solubility
DMSO:40 mg/mL (115.9 mM)
Smiles
O=C1N=C (C=CC=2C=CC=C (Br) C2) C=C (N1) C (F) (F) F
Molecular Formula
C13H8BrF3N2O
Molecular Weight
345.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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