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UC-764864

UC-764864 is a selective UBE2N inhibitor that blocks E1-UBE2N thioester transfer, reducing UBE2N ubiquitination. It inhibits innate immune signaling and demonstrates cytotoxic effects in MDS/AML cell lines and primary cells, making it a valuable tool for leukemia research.

Product Specifications

CAS Number

278806-03-4

Product Name Alternative

E3Enzyme, E3 Enzyme, E2Enzyme, E2 Enzyme, E1Enzyme, E1 Enzyme, UBE2N

Field of Research

Protein Biochemistry

Purity

99.30% (May vary between batches)

Solubility

DMSO:100 mg/mL (310.15 mM)

Smiles

O=C (C=CSC1=NC=2C=C (C=CC2N1) C) C3=CC=C (C=C3) CC

Molecular Formula

C19H18N2OS

Molecular Weight

322.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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