FEN1-IN-7
FEN1-IN-7 is a potent and selective inhibitor of Flap endonuclease-1 (FEN1; IC50=18 nM) with weaker activity against XPG (IC50=3.04 μM) . This small molecule disrupts DNA repair pathways, sensitizing cancer cells to DNA-damaging agents like alkylators in cellular studies, making it a valuable research tool for investigating combination therapies.
Product Specifications
CAS Number
824983-90-6
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Smiles
C (N1C2=C (C (=O) N (O) C1=O) C (C) =CS2) C=3C=C4C (=C (OC) C3) OCO4
Molecular Formula
C16H14N2O6S
Molecular Weight
362.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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