MS934
MS934 is a potent, novel VHL-recruiting degrader of MEK1/2, demonstrating strong anti-proliferative activity with a GI50 of 0.023 μM in HT-29 cells. It is a valuable research tool for investigating multiple cancer types, including melanoma, NSCLC, colorectal cancer, and hepatocellular carcinoma, in both in vitro and in vivo studies.
Product Specifications
CAS Number
2756323-15-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C ([C@@H] (NC (CCCCCCCCCCCNCCCCONC (=O) C1=C (NC2=C (F) C=C (I) C=C2) C (F) =C (F) C=C1) =O) [C@] (C) (C) C) (=O) N3[C@H] (C (N[C@@H] (C) C4=CC=C (C=C4) C5=C (C) N=CS5) =O) C[C@@H] (O) C3
Molecular Formula
C52H69F3IN7O6S
Molecular Weight
1104.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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