CK1-IN-2
CK1-IN-2 (compound 4) is a potent, selective casein kinase 1 (CK1) inhibitor, demonstrating low nanomolar IC50 values against CK1α, δ, and ε isoforms. It is a valuable research tool for studying DUX4 biology and has been utilized in cellular and animal models of facioscapulohumeral muscular dystrophy (FSHD) .
Product Specifications
CAS Number
1383376-92-8
Product Name Alternative
CaseinKinase, Casein Kinase
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.31% (May vary between batches)
Solubility
DMSO:40 mg/mL (129.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.47 mM)
Smiles
O=C1OCC2=NC=CC (C3=CN (N=C3C=4C=CC (F) =CC4) C) =C12
Molecular Formula
C17H12FN3O2
Molecular Weight
309.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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