PROTAC PTPN2 degrader-2
PROTAC PTPN2 degrader-2 (example 187B) is a potent and selective small molecule degrader of PTPN2, a phosphatase implicated in oncology and immunometabolism. Its utility has been demonstrated in cellular assays for cancer immunotherapy research and shows potential for in vivo metabolic disease studies.
Product Specifications
CAS Number
2912307-38-9
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1C2=C3C (N1[C@@H]4C (=O) NC (=O) CC4) =CC=C (C3=CC=C2) C5CCN (C (NC6=CC (CS (=O) (=O) N7C (C) (C) C[C@@H] (NC8=CC (=CC=C8) C9=C (Cl) C (OCC (O) =O) =C (C (O) =O) S9) CC7) =CC=C6) =O) CC5
Molecular Formula
C49H49ClN6O11S2
Molecular Weight
997.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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