PROTAC PTPN2 degrader-2 TFA
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent and selective degrader of the PTPN2 phosphatase. Its utility in oncology and metabolic disease research is supported by studies demonstrating target degradation in both cellular and in vivo models, offering a tool for investigating these pathways.
Product Specifications
CAS Number
2912307-39-0
Field of Research
Immunology & Inflammation; Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (C (O) =O) (F) (F) F.O=C1C2=C3C (N1[C@@H]4C (=O) NC (=O) CC4) =CC=C (C3=CC=C2) C5CCN (C (NC6=CC (CS (=O) (=O) N7C (C) (C) C[C@@H] (NC8=CC (=CC=C8) C9=C (Cl) C (OCC (O) =O) =C (C (O) =O) S9) CC7) =CC=C6) =O) CC5
Molecular Formula
C51H50ClF3N6O13S2
Molecular Weight
1111.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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