DQn-1
DQN-1 is a potent antifolate compound with significant antitubercular activity, exhibiting an MIC90 of 0.03 μM against Mycobacterium tuberculosis. It acts as a potent inhibitor of both Mtb and human DHFR enzymes, with IC50 values in the low nanomolar range. This inhibitor is a valuable tool for investigating folate metabolism in tuberculosis research, including in vitro enzyme inhibition and whole-cell antibacterial studies.
Product Specifications
CAS Number
57343-54-1
Field of Research
Infectious Disease & Virology
Smiles
ClC=1C2=C (C=CC1CNC3=CC=C (C (O) =O) C=C3) N=C (N) N=C2N
Molecular Formula
C16H14ClN5O2
Molecular Weight
343.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1305318-01 0.02 mg (E-Coli)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details 
MBS1305318-02 0.1 mg (E-Coli)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details MBS1305318-03 0.02 mg (Yeast)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details MBS1305318-04 0.1 mg (Yeast)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details MBS1305318-05 0.02 mg (Baculovirus)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details MBS1305318-06 0.02 mg (Mammalian-Cell)
Recombinant Cupriavidus necator Probable GTP-binding protein EngB (engB)
Sign In for Pricing
View Details