DQn-1
DQN-1 is a potent antifolate compound with significant antitubercular activity, exhibiting an MIC90 of 0.03 μM against Mycobacterium tuberculosis. It acts as a potent inhibitor of both Mtb and human DHFR enzymes, with IC50 values in the low nanomolar range. This inhibitor is a valuable tool for investigating folate metabolism in tuberculosis research, including in vitro enzyme inhibition and whole-cell antibacterial studies.
Product Specifications
CAS Number
57343-54-1
Field of Research
Infectious Disease & Virology
Smiles
ClC=1C2=C (C=CC1CNC3=CC=C (C (O) =O) C=C3) N=C (N) N=C2N
Molecular Formula
C16H14ClN5O2
Molecular Weight
343.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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