BMPR2-IN-1

BMPR2-IN-1 (Compound 8a) is a potent and selective BMPR2 inhibitor with a Kd of 83.5 nM. This small molecule is a valuable research tool for investigating the role of BMPR2 signaling in diseases such as pulmonary arterial hypertension, Alzheimer's disease, and cancer, in both cellular and animal models.