Mcl-1 inhibitor 16

Mcl-1 Inhibitor 16 is a platinum-based, mitochondria-targeting compound that potently inhibits Mcl-1, triggering Bax/Bak-dependent apoptosis. It demonstrates antitumor efficacy in vitro and in vivo, supporting its investigation as a single agent or in combination with venetoclax (ABT-199) for cancer research.