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Antiproliferative agent-25

Antiproliferative Agent-25 (Compound 3s4) is a potent and selective PRMT5 inhibitor (IC50 = 0.11 μM) that binds the SAM site. It increases hnRNP E1 levels, induces apoptosis, and inhibits migration in A549 cells in vitro, though it exhibits high metabolic clearance in liver microsome assays.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin

Molecular Formula

C20H21BrN2O2

Molecular Weight

401.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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