Antiproliferative agent-25
Antiproliferative Agent-25 (Compound 3s4) is a potent and selective PRMT5 inhibitor (IC50 = 0.11 μM) that binds the SAM site. It increases hnRNP E1 levels, induces apoptosis, and inhibits migration in A549 cells in vitro, though it exhibits high metabolic clearance in liver microsome assays.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin
Molecular Formula
C20H21BrN2O2
Molecular Weight
401.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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