PROTAC BTK Degrader-5
PROTAC BTK Degrader-5 (Compound 3e) is a potent and selective degrader of Bruton's tyrosine kinase (BTK) with a DC50 of 7.0 nM in JeKo-1 cells. It demonstrates antiproliferative activity in lymphoma cell lines and shows potential for research in B-cell malignancies, including chronic lymphocytic leukemia (CLL) .
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C52H57ClFN9O6
Molecular Weight
958.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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