CNBCA
CNBCA is a potent and selective competitive SHP2 inhibitor with an IC50 of 0.87 μM. It suppresses SHP2 enzymatic activity, downstream pAkt/pERK signaling, and inhibits proliferation in breast cancer cell lines like BT474 and MDA-MB-468, supporting its use in oncology research.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C26H34O5
Molecular Weight
426.55
Storage Conditions
-20°C
Notes
For research use only.
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SQSTM1 (Sequestosome-1, EBI3-associated Protein of 60kD, EBIAP, p60, ORCA, OSIL, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, Ubiquitin-binding Protein p62)
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