EGFR-IN-81

EGFR-IN-81 is a potent small molecule inhibitor of both wild-type EGFR and the L858R/T790M mutant, with IC50 values in the low nanomolar range. It also demonstrates cytotoxic activity against MCF-7 and HCT116 cancer cell lines in vitro, making it a useful research tool for studying EGFR-driven oncogenesis and resistance mechanisms.