P-gp/BCRP-IN-2

P-gp/BCRP-IN-2 is a potent dual inhibitor of P-glycoprotein (IC50 1.6 nM) and BCRP (IC50 600 nM) . This oxadiazole compound enhances the efficacy of chemotherapeutics like Doxorubicin in resistant cancer cell models, supporting research into overcoming multidrug resistance in oncology.