PRMT4-IN-3

PRMT4-IN-3 (compound 56) is a potent and selective class I PRMT inhibitor, demonstrating high potency against PRMT4 (IC50 = 37 nM) and moderate activity against PRMT6 (IC50 = 253 nM) . This small molecule is a valuable chemical probe for investigating arginine methylation in cancer biology and epigenetics research, both in vitro and in cellular models.