CBP/p300-IN-21
CBP/p300-IN-21 (Compound 5d) is a selective small molecule inhibitor of the CBP and p300 acetyltransferases, demonstrating potent activity against p300 (IC50 = 0.07 μM) and CBP (IC50 = 1.755 μM) . It effectively reduces cellular H3K18 acetylation and has shown in vivo efficacy by inhibiting the growth of 4T1 murine breast tumors.
Product Specifications
CAS Number
1065581-69-2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
OC=1C=C2C=C3C=4C (=CC5=C (C4) OCO5) CC[N+]3=CC2=CC1OC.[Cl-]
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
Storage Conditions
-20°C
Notes
For research use only.
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