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DCLK1-IN-2

DCLK1-IN-2 (Compound I-5) is a potent small molecule inhibitor of DCLK1 with an IC50 of 171.3 nM. It demonstrates robust in vitro antiproliferative activity against SW1990 pancreatic cancer cells (IC50 = 0.6 μM) and has shown promising in vivo antitumor efficacy in research models.

Product Specifications

CAS Number

2978517-43-8

Field of Research

Protein Biochemistry, Signal Transduction

Smiles

N (C1=C2C (=NC (NC3=C (OC) C=C (C=C3) N4CCN (C) CC4) =N1) N=CN2) C5=C (S (C (C) C) (=O) =O) C=CC=C5

Molecular Formula

C26H32N8O3S

Molecular Weight

536.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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