DCLK1-IN-2
DCLK1-IN-2 (Compound I-5) is a potent small molecule inhibitor of DCLK1 with an IC50 of 171.3 nM. It demonstrates robust in vitro antiproliferative activity against SW1990 pancreatic cancer cells (IC50 = 0.6 μM) and has shown promising in vivo antitumor efficacy in research models.
Product Specifications
CAS Number
2978517-43-8
Field of Research
Protein Biochemistry, Signal Transduction
Smiles
N (C1=C2C (=NC (NC3=C (OC) C=C (C=C3) N4CCN (C) CC4) =N1) N=CN2) C5=C (S (C (C) C) (=O) =O) C=CC=C5
Molecular Formula
C26H32N8O3S
Molecular Weight
536.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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