INF200
INF200 (compound 5) is a sulfonylurea-based NLRP3 inflammasome inhibitor. In vitro, it reduces IL-1β secretion from human macrophages at 10 μM. In vivo, it improves cardiometabolic parameters, reduces systemic inflammation, and protects against cardiac dysfunction in a rat model of diet-induced metaflammation and ischemia/reperfusion injury.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation
Molecular Formula
C13H13ClN2O4
Molecular Weight
296.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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