Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is a small molecule targeting Leishmania donovani, exhibiting potent in vitro activity (IC50 3.39 μM) by inhibiting prolyl-tRNA synthetase and host IL-10 signaling. It induces autophagy-mediated apoptosis in promastigotes and has demonstrated efficacy in reducing parasite burden in animal infection models.
Product Specifications
Field of Research
Infectious Disease & Virology
Molecular Formula
C22H18N4O3
Molecular Weight
386.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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