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FD1024

FD1024 is a potent small molecule inhibitor of PIM kinases (PIM1/2/3 IC50s: 1.96-38.9 nM) . It exhibits strong antiproliferative activity against AML cell lines like MV-4-11 and demonstrates in vivo antitumor efficacy in murine models, supporting its use in oncology and hematological cancer research.

Product Specifications

CAS Number

1422456-47-0

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

FC1=C (C (F) =CC=C1) C2=NC (C (NC=3C (O[C@H]4CC[C@H] (N) CC4) =CC=NC3) =O) =CS2

Molecular Formula

C21H20F2N4O2S

Molecular Weight

430.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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