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PEX5-PEX14 PPI-IN-1

PEX5-PEX14 PPI-IN-1 (Compound 8) is a small molecule inhibitor that disrupts the PEX5-PEX14 protein-protein interaction with a Ki of 53 μM. It exhibits antitrypanosomal activity against Trypanosoma brucei brucei bloodstream forms with an EC50 of 5 μM, making it a useful chemical probe for studying peroxisomal import and parasite biology in vitro.

Product Specifications

Field of Research

Infectious Disease & Virology

Smiles

O=C1[C@H] (CC2=CNC3=C2C=CC=C3) NCCCN1[C@@H] (CC4=CNC5=C4C=CC=C5) C (OC) =O

Molecular Formula

C26H28N4O3

Molecular Weight

444.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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