RORγ antagonist 1
RORγ antagonist 1 is a potent betulinic acid derivative functioning as a RORγ antagonist (K D = 0.18 μM) . It exhibits anti-proliferative activity in pancreatic cancer models, suppressing RAS/MAPK and AKT/mTORC1 pathways while inducing caspase-dependent apoptosis in vitro and in vivo.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C35H60N2O2
Molecular Weight
540.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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