RORγt inverse agonist 31
RORγt inverse agonist 31 (14g) is a potent and selective RORγt antagonist with an IC50 of 0.428 μM. It effectively reduces psoriasiform inflammation in Imiquimod-induced mouse models, making it a valuable tool for studying Th17-driven autoimmune diseases in both in vitro and in vivo research.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C23H15Cl2F3N4O3S
Molecular Weight
555.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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