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RORγt inverse agonist 31

RORγt inverse agonist 31 (14g) is a potent and selective RORγt antagonist with an IC50 of 0.428 μM. It effectively reduces psoriasiform inflammation in Imiquimod-induced mouse models, making it a valuable tool for studying Th17-driven autoimmune diseases in both in vitro and in vivo research.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C23H15Cl2F3N4O3S

Molecular Weight

555.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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