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IRAK4-IN-27

IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor with an IC50 of 8.7 nM. It suppresses proliferation and induces apoptosis in MYD88 L265P mutant DLBCL cells in vitro, making it a valuable tool for investigating TLR/IL-1R signaling pathways in oncology research.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Molecular Formula

C23H22N6O3

Molecular Weight

430.46

Storage Conditions

-20°C

Notes

For research use only.

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