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SA-VA

SA-VA is an intracellular self-assembling PROTAC designed for the selective degradation of VEGFR-2 and EphB4. It is activated in situ via a copper-catalyzed click reaction utilizing endogenous tumor copper, inducing S-phase cell cycle arrest and apoptosis in U87 glioblastoma cells for targeted cancer research.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C50H53ClF3N11O7S

Molecular Weight

1044.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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