ET receptor antagonist 2
Compound 16j is a potent, orally bioavailable endothelin receptor antagonist with an IC50 of 0.22 nM. It is a valuable research tool for pulmonary arterial hypertension, demonstrated to ameliorate disease progression in monocrotaline-induced rat models of PAH.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C22H25N5O5S
Molecular Weight
471.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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